FLCCC COVID Treatment Protocols

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FLCCC | Front Line COVID-19 Critical Care Alliance

COVID-19 is a treatable disease, when caught early and treated appropriately. While there is no “magic bullet,” a number of therapies and drugs with different mechanisms of action have been shown to work during various phases of the disease.

The protocols on this page represent our recommended approaches based on the best and most recent literature. The information is provided as guidance to healthcare providers worldwide and should only be used by medical professionals in formulating their approach to COVID-19. Patients should always consult with their provider before starting any medical treatment. Please do not consider these protocols as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor, share the information on this website and discuss with her/him. Please review our disclaimers, and visit our get started guide for information on how to find physicians who follow our protocols as well as information you can share with your healthcare provider.

As this is a highly dynamic topic, we will update these guidelines as new information emerges. Please check to ensure you are using the latest version of this protocol. You may need to clear your computer’s cache if you have visited the site previously.

Treatment Protocols

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©2020–2022 All Rights Reserved FLCCC Alliance. The information contained or presented on this website is for educational purposes only. Information on this site is NOT intended to serve as a substitute for diagnosis, treatment, or advice from a qualified, licensed medical professional. The facts presented are offered as information only in order to empower you – our protocol is not medical advice – and in no way should anyone infer that we, even though we are physicians, or anyone appearing in any content on this website are practicing medicine, it is for educational purposes only. Any treatment protocol you undertake should be discussed with your physician or other licensed medical professional. Seek the advice of a medical professional for proper application of ANY material on this site or our program to your specific situation. NEVER stop or change your medications without consulting your physician. If you are having an emergency contact your emergency services: in the USA that’s 911. Please read our complete disclaimers.

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Resource: https://covid19criticalcare.com/treatment-protocols/

Ivermectin, a potential anticancer drug derived from an antiparasitic drugMingyang Tang, Xiaodong Hu, […], and Qiang Fang

Graphical abstract

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, autophagy and pyroptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.

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Abbreviations: ASC, Apoptosis-associated speck-like protein containing a CARD; ALCAR, acetyl-L-carnitine; CSCs, Cancer stem cells; DAMP, Damage-associated molecular pattern; EGFR, Epidermal growth factor receptor; EBV, Epstein-Barr virus; EMT, Epithelial mesenchymal-transition; GABA, Gamma-aminobutyric acid; GSDMD, Gasdermin D; HBV, Hepatitis B virus; HCV, Hepatitis C virus; HER2, Human epidermal growth factor receptor

SOURCE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/

Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth

Shican Zhou 1Hang Wu 1Wenjuan Ning 1Xiao Wu 1Xiaoxiao Xu 1Yuanqiao Ma 1Xingwang Li 1Junhong Hu 1Chenyu Wang 1Junpeng Wang 1

Affiliations expand

Free PMC article


Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. Ivermectin, an antiparasitic drug, has been shown to possess anti-inflammation, anti-virus, and antitumor properties. However, whether ivermectin affects CRC is still unclear. The objective of this study was to evaluate the influence of ivermectin on CRC using CRC cell lines SW480 and SW1116. We used CCK-8 assay to determine the cell viability, used an optical microscope to measure cell morphology, used Annexin V-FITC/7-AAD kit to determine cell apoptosis, used Caspase 3/7 Activity Apoptosis Assay Kit to evaluate Caspase 3/7 activity, used Western blot to determine apoptosis-associated protein expression, and used flow cytometry and fluorescence microscope to determine the reactive oxygen species (ROS) levels and cell cycle. The results demonstrated that ivermectin dose-dependently inhibited colorectal cancer SW480 and SW1116 cell growth, followed by promoting cell apoptosis and increasing Caspase-3/7 activity. Besides, ivermectin upregulated the expression of proapoptotic proteins Bax and cleaved PARP and downregulated antiapoptotic protein Bcl-2. Mechanism analysis showed that ivermectin promoted both total and mitochondrial ROS production in a dose-dependent manner, which could be eliminated by administering N-acetyl-l-cysteine (NAC) in CRC cells. Following NAC treatment, the inhibition of cell growth induced by ivermectin was reversed. Finally, ivermectin at low doses (2.5 and 5 µM) induced CRC cell arrest. Overall, ivermectin suppressed cell proliferation by promoting ROS-mediated mitochondrial apoptosis pathway and inducing S phase arrest in CRC cells, suggesting that ivermectin might be a new potential anticancer drug therapy for human colorectal cancer and other cancers.

Keywords: apoptosis; cell cycle; colorectal cancer; ivermectin; oxidative stress.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.


FIGURE 1 The chemical structure of ivermectin…
FIGURE 2 Ivermectin inhibits cell proliferation of…
FIGURE 3 The effect of ivermectin on…
FIGURE 4 Ivermectin induced apoptosis in colorectal…
FIGURE 5 Effect of ivermectin on Caspase…

SOURCE: https://pubmed.ncbi.nlm.nih.gov/34483925/

Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes

Na Li and Xianquan Zhan

Additional article information

Associated Data

Supplementary Materials



Ivermectin, as an old anti-parasite drug, can suppress almost completely the growth of various human cancers, including ovarian cancer (OC). However, its anticancer mechanism remained to be further studied at the molecular levels. Ivermectin-related molecule-panel changes will serve a useful tool for its personalized drug therapy and prognostic assessment in OCs.


To explore the functional significance of ivermectin-mediated lncRNA-EIF4A3-mRNA axes in OCs and ivermectin-related molecule-panel for its personalized drug therapy monitoring.


Based on our previous study, a total of 16 lncRNA expression

SOURCE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272521/#!po=1.31579

New Study on Ivermectin ‘Should Convince Any Naysayer’: Dr. Pierre Kory

According to Dr. Pierre Kory, a new study proves that ivermectin effectively prevents the transmission of COVID-19.

During a six-month study in 2020, residents of the Brazilian city of Itajai were given ivermectin upon request. Scientists found that the 100,000 participants in the study were 44 percent less likely to contract COVID-19. 

Cureus published  the peer-reviewed study on Jan. 15.

Dr. Pierre Kory, president of the Front Line COVID-19 Critical Care Alliance (FLCCC) told the Epoch Times the results of the study “should convince any naysayer,” adding, “what they found was astounding.”

The study, conducted between July 7 and Dec. 2, 2020, also showed that users of ivermectin enjoyed a statistically significant decrease in hospitalization and mortality.

The FDA and CDC have resisted authorizing the use of ivermectin. Some say their continued refusal to make the drug available is inexplicable, particularly after medical officials noted positive treatment results in India and Japan.

Pressure to allow ivermectin as a preventative or treatment medication for COVID in the United States is mounting. Prominent voices, such as Dr. Robert Malone, the inventor of the nine original mRNA vaccine patents, and podcaster Joe Rogan have encouraged political and medical officials to advocate its use.

Dr. Kory is astounded by the lack of reporting on the peer-reviewed study.

“You would think this would lead major headlines everywhere. And yet, nothing. And this is not new, this censorship of this highly effective science and evidence around repurposed drugs. The censoring of it, it’s not new, it’s just getting more and more absurd. And it has to stop,” he said.

Dr. Gideon Meyerowitz-Katz, an Australian epidemiologist, is not convinced. The Epoch Times reports he referred to Dr. Kory’s study as “a fairly simple example of observational research that you’d do on routine medical data” and suggested the controls for the study (designed to mitigate error) were “pretty inadequate given the purpose.”

The Food and Drug Administration has approved ivermectin for certain uses, but not for use against COVID-19. 

Many have complained that hospitals will not administer ivermectin. Others are concerned that pharmacies will not fill a prescription for ivermectin, even if prescribed by an in-network physician.



– Attorney Renz

Attorney Thomas Renz speaking at Clay Clark’s ReAwaken America Tour in Michigan says he is constantly contacted by families across America who have loved ones being killed by the hospital protocols that Fauci instituted in all US hospitals. The Remdesivir + Ventilator protocol finds people dying, and hospitals making Covid money. You have Medical Rights!


Click photo to watch
You Must Fight For Your Families in Hospitals

During this speech Attorney Renz gives you several key pieces of information on how to fight hospitals and why you must fight for your family members.

1- Do not let the hospitals isolate your family members from you.

2 – Remdesivir and Ventilators equal death for your hospitalized family member. That is the Fauci protocol.

3 – Remdesivir and Ventilators equal death is key.

Ivermectin, Hydroxychloroquine, and Budesonide work.

Go here for protocols that work:
The Math+ and I-Mask+ protocols that Renz references in his speech are here:



Another great treatment resource is PATIENT TREATMENT GUIDE E-BOOKLET AND DOWNLOAD PAGE. https://www.truthforhealth.org/patient-treatment-guidehttps://www.truthforhealth.org/patient-treatment-guide